This might give some clues for a solution even though it refers to CVS, a different piece of software:
http://www.damirscorner.com/NOD32CVSNTC ... oblem.aspx
This
Google search may help with configuring NOD32 or the program's own included documentation - you have to allow access for localhost and the ports XAMPP uses in the NOD32 IMON perhaps using the NOD32 Control Center - which may be blocked by default.
(
I don't have this software installed but you will know what I mean here).
I found this FAQ dated August 2007 which may be of help to you:
http://computersecurityassociates.com/faq/nod32_faq.htm
The NOD32 web site may also hold a solution for your issue especially those related to Vista.
Remember in Vista you have to be logged in as an administrator and do anything useful as an administrator, often accessing a context menu by a right click on the file you wish to access for changes and selecting 'run as administrator'.