Is it possible to use XAMPP with default configuration on a

[BlackHalt]

Is it possible to use XAMPP with default configuration on a production server?

YES / NO

[Izzy]

Yes - if you like taking security risks.
No - not recommended for a production server because of the security risks even after following those measures outlined in the readme file below.

xampp\readme_en.txt file under section:
A matter of security (A MUST READ!)

The term used for securing a production server is hardening and these Google results may help.